Big Data: A great challenge for genomics

genomics
Genomics

One of the consequences that the genomic era has brought is the generation of large amounts of data. Just imagine that the human DNA information consists of about 3,200 million letters makes it clear that for its analysis does not reach a personal computer.

genome
genome

Today, the routine integration of genomics into scientific research has resulted in the generation of information about the DNA of microorganisms, higher organisms, human genomes of healthy and sick individuals, tumors and other tissues. As a result, massive amounts of data are generated daily that require storage and routine analysis.

This has become one of the great bottlenecks of the genomic revolution. If we look for the reading of the human genome to become a routine tool for health care, as well as tools for the discovery of the causes and treatments of the most frequent diseases, it will be necessary to develop strategies that allow storage, access and Analysis of genomic data quickly and efficiently no matter where in the world they are generated.

Researchers in life sciences have recently joined the Big Data club, a term coined long ago for other disciplines that generate large amounts of data. Among them, astronomy and physics related to the study of high energy density particles.

Big Data is a term applied to data sets that exceed the capacity of the usual software to be stored, processed and mobilized in a reasonable time. Under the concept of Big Data the size of each data set is constantly increasing. In 2012, the size of a data set was dimensioned from a dozen terabytes to several pentabytes. In this way a small genomic laboratory can quickly become a generator of Big Data.

human

Even more, Researchers consulted several genomic information banks several times a day, for example, the IEB received about nine million online queries daily during 2012, which represents an increase of 60% compared to the previous year. To address this challenge, various strategies have emerged, among which “cloud computing” is particularly attractive when financial resources are limited for the construction of expensive IT infrastructure in each research center.

Technically the cloud, which comes from English cloud computing, refers to the processing and massive storage of data in servers (computers) that host the information of multiple centers in order to have instant and permanent access to the databases regardless of the geographical location of the user. The cloud was created for people who are not experts in computer science in order to answer complex questions quickly and easily. Currently, the cloud is used daily when checking e-mail or banking movements from a personal computer. However, its use for the management of genomic Big Data begins to develop successfully in various parts of America, Europe and Asia.

In this way, to answer scientific questions such as the interaction of microorganisms with the human body, the molecular mechanisms of common diseases, the identification of new treatments for some types of cancer or the way in which patients respond to common treatments, it will be increasingly common to access large banks of genomic information, use sophisticated algorithms and perform data analysis from our personal terminals, without having to generate our own sophisticated IT infrastructure or have the support of computer experts. This is how biological research that uses genomic information becomes more and more a computational activity, analyzing gigantic amounts of data from the comfort of our personal computers.

It will be increasingly common to access large banks of genomic information, use sophisticated algorithms and perform data analysis from our personal terminals, without having to generate our own sophisticated IT infrastructure or have the support of computer experts. This is how biological research that uses genomic information becomes more and more a computational activity, analyzing gigantic amounts of data from the comfort of our personal computers. It will be increasingly common to access large banks of genomic information, use sophisticated algorithms and perform data analysis from our personal terminals, without having to generate our own sophisticated IT infrastructure or have the support of computer experts.

This is how biological research that uses genomic information becomes more and more a computational activity, analyzing gigantic amounts of data from the comfort of our personal computers.

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